Magnetic Diagnostic Assay for Neurodegenerative Diseases

  • ebri image NGF
  • Altzheimer s Disease
  • MADIA slideshow
  • Pathological Cascade

MADIA will develop a versatile and cost-effective in-vitro tool for early diagnosis of Alzheimer’s and Parkinson’s diseases. Alzheimer’s and Parkinson’s diseases, the two most common neurodegenerative disorder worldwide, are debilitating and largely untreatable conditions that are strongly linked with age.


 "MADIA does not stop and this site does not close!

MADIA has concluded its EC engaged and funded work on March 31st 2020.

The project has successfully fulfilled its main objectives – it has entirely demonstrated the highest diagnostic potential of the proposed technology, confirming the most ambitious objectives, such as fg/ml detection capability. Most partners of the consortium are interested to upgrade further the developed technologic devices, bringing them to a pre-commercial prototype level. Formal agreements between different partners and groups of partners are being established to proceed on this route.

Stay in touch, visit our site for future updates and developments."

 - Project Coordinator – Valentin Alek Dediu - 



Events

MADIA FINAL PROJECT MEETING

The MADIA Final project meeting was held on 20th  and 21st  February 2019 in Bologna, Italy and it has been the occasion to verify all together with the last achievements Madia related but also to thank each other for the great cooperation experienced during the (more than) 3 years’ Project and to plan fruitful collaborations in the next future!

 


  • September 21st every year is World Alzheimer's Day around the world.
    We share with you the short film "Ogni giorno" (Every day) by Francesco Felli.




Alzheimer’s is the most common form of dementia, affecting seven million across Europe. The global cost of dementia in 2015 was around US$ 820 billion, meaning that age-related neurodegenerative disease is one of the largest medical and societal challenges faced by our society.

Costs of dementia in 2015 (billion US$), by G7 and G20 country classification

Costs of dementia in 2015 (billion US$), by G7 and G20 country classification


(Source: World Alzheimer Report 2015 - The Global Impact of Dementia: An analysis of prevalence, incidence, cost and trends.)


 

The MADIA technology

The MADIA technology

MADIA aims at fabricating devices based on arrays of magnetic sensors integrated into a microfluidics device and capable of recognising biomarkers, obtained from cerebrospinal fluid or blood samples, conjugated with ultra-small magnetic nanoparticles.


This will allow the early diagnosis of Alzheimer’s and Parkinson’s diseases and improve the efficacy of current therapies which have been shown to slow the progression, particularly of Parkinson’s disease, as currently there is no cure for either disease.

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